Our knowledge base workgroup is developing an open-source repository of standardized evidence about drug-outcome relationships from disparate sources, including published literature, product labeling, spontaneous adverse event reporting, and existing bio-medical ontologies. The knowledge base will serve as the primary source to enable the construction of test cases (positive controls and negative controls) to facilitate systematic evaluation of method performance. These positive and negative controls will serve as reference sets for both methodological evaluation, as well as for empirical calibration of unknown effects.
As a reference set is developed and released, we will post details on this page, so check back regularly…
