Weekly OHDSI Digest- December 5, 2022

WEEKLY COMMUNITY CALL MEETINGS

Please join us Tuesday, Dec. 6 (11 am ET), for our next OHDSI community call, when we will learn more about recent studies that have come out of our global community. We will hear about the following studies:

• Integrating real-world data from Brazil and Pakistan into the OMOP common data model and standardized health analytics framework to characterize COVID-19 in the Global South – Sara Khalid (University Research Lecturer, Senior Research Fell in Biomedical Data Science and Health Informatics, University of Oxford)

• Comparative risk of thrombosis with thrombocytopenia syndrome or thromboembolic events associated with different covid-19 vaccines: international network cohort study from five European countries and the US – Xintong Li (PhD student, University of Oxford)

• Transforming and evaluating the UK Biobank to the OMOP Common Data Model for COVID-19 research and beyond – Václav Papež (Research Associate, UCL Institute of Health Informatics)

• Adjusting for indirectly measured confounding using large-scale propensity score – Linying Zhang (PhD student, Columbia University)

• PheValuator 2.0: Methodological improvements for the PheValuator approach to semi-automated phenotype algorithm evaluation – Joel Swerdel (Associate Director of Epidemiology Analytics, Janssen Research and Development)

Everybody is invited. Calendar invites for our 2022 community calls go out each Friday. If you did not receive one, please use this link to join the meeting. All recordings from these weekly meetings will be posted on both our main OHDSI Teams tenant and on our OHDSI.org Community Calls page.

WEEKLY WORKING GROUP MEETINGS

Common Data Model WG: Tuesday, Dec. 6 at 10am ET (Meeting Link )
Meetings are traditionally scheduled for the first and third Tuesdays of each month at 10am and 1pm ET, respectively

Psychiatry WG: Wednesday, Dec. 7 at 8am ET (Meeting Link)
Meetings are traditionally scheduled for the first Wednesday of each month at 8am ET.

Atlas WG: Wednesday, Dec. 7 at 9am ET (Meeting Link)
Meetings are traditionally scheduled for the first Wednesday of each month at 9am ET.

FHIR and OMOP WG- Digital Quality Measurements Subgroup: Wed, Dec. 7 at 10am ET (Meeting Link)
Meetings are traditionally scheduled for every other Wednesday at 10am ET. NOTE: This meeting takes place on Zoom but please check the Teams Work Group for information and updates (Meeting ID: 836 4585 6405; Passcode: 552204)

Open-Source Community WG: Wednesday, Dec. 7 at 11am ET (Meeting Link)
Meetings are traditionally scheduled for every other Wednesday at 11am ET.

Health Equity Work Group: Wednesday, Dec. 7 at 12pm ET (Meeting Link)
Meetings are traditionally scheduled for the first Wednesday of the month at 12pm ET.

FHIR and OMOP WG – Data Model Harmonization Subgroup: Wednesday, Dec. 7 at 2pm PST (Western Hemisphere) (Meeting Link) Meetings are traditionally scheduled for the 1st Wednesday of the month at 2pm PST. NOTE: This meeting takes place on Zoom but please check the Teams Work Group for information and updates (Meeting ID:926 6488 5488; Passcode: 551570) THIS MEETING TAKES PLACE AT 4PM

Pop. Level Estimation WG Meeting (Eastern Hemi): Wednesday, Dec. 7 at 4pm KST (2AM ET) (Meeting Link)**Meetings are traditionally scheduled for the first Wednesday of every month at 4pm KST.

Dentistry WG: Thursday, Dec. 8 at 7pm ET (Meeting Link)
Meetings are traditionally scheduled for every Thursday at 7pm ET.

Education WG: Friday, Dec. 30 at 9am ET (Meeting Link)
Meetings are traditionally scheduled for every 4 weeks on Friday of each month at 9am ET.

GIS-Geographic Information System WG DEVELOPMENT Meeting: Friday, Dec. 9 at 9am ET (Meeting Link)
Meetings are traditionally scheduled for every other Friday at 9am ET.

Phenotype Development and Evaluation WG: Friday, Dec. 9 at 9am ET (Meeting Link)
Meetings are traditionally scheduled for the second and fourth Fridays of each month at 9am ET.

Clinical Trials WG: Friday, Dec. 9 at 10:15am ET (Meeting Link)
Meetings are traditionally scheduled for every other Friday at 10:15am ET. THIS MEETING WILL BE AT 11AM

OHDSI SHOUTOUTS

Congratulations to the team of Veronika Pav, Andrew Burns, Courtney Colahan, Brian Robison, Jacob Kean, and Scott DuVall on the publication of Illustration of Continuous Enrollment and Beneficiary Categorization in DoD and VA Infrastructure for Clinical Intelligence in Military Medicine.

• Congratulations to the team of Berta Raventós, Alicia Abellan, Andrea Pistillo, Carlen Reyes, Edward Burn, and Talita Duarte-Salles on the publication of Impact of the COVID-19 pandemic on eating disorders diagnoses among adolescents and young adults in Catalonia: A population-based cohort study in the International Journal of Eating Disorders.

• Congratulations to the team of Edward Burn, Elena Roel, Andrea Pistillo, Sergio Fernández-Bertolín, Maria Aragón, Berta Raventós, Carlen Reyes, Katia Verhamme, Peter Rijnbeek, Xintong Li, Victoria Y. Strauss, Daniel Prieto-Alhambra, and Talita Duarte-Salles on the publication of Thrombosis and thrombocytopenia after vaccination against and infection with SARS-CoV-2 in Catalonia, Spain in Nature Communications.

• Congratulations to the team of Edward Burn, Xintong Li, Antonella Delmestri, Nathan Jones, Talita Duarte-Salles, Carlen Reyes, Eugenia Martinez-Hernandez, Edelmira Marti, Katia M. C. Verhamme, Peter R. Rijnbeek, Victoria Y. Strauss, and Daniel Prieto-Alhambra on the publication of Thrombosis and thrombocytopenia after vaccination against and infection with SARS-CoV-2 in the United Kingdom in Nature Communications.

• Congratulations to Anna Ostropolets, who successfully defended her dissertation at Columbia University last week. Her dissertation title was “Generating Reliable and Responsive Observational Evidence: Reducing Pre-analysis Bias.”

JOB POSTINGS

Northeastern University invites applications for multiple tenured/ tenure-track faculty positions in support of an Impact Engine centered on large-scale observational health data science and informatics to start in the fall of 2023. These faculty will be core members of our Real-World Healthcare Navigator (RWHN) Impact Engine which aims to change how research is translated into clinical practice by establishing a sustainable service that leads the way in fully reproducing health studies (Real-World Healthcare Navigator | Impact Engines). Successful candidates will work closely with the OHDSI Center at Northeastern’s Roux Institute to develop and apply healthcare analytics in the real-world evidence (RWE) area with the goal of improving patient health outcomes. More information and an application link are available here.

 The OHDSI Center at the Roux Institute seeks a postdoctoral fellow to join their team focused on developing statistical methods and applying them to observational data from large-scale federated datasets (e.g. electronic health records and administrative claims data), with specific applications to the safety of biologics. This research will directly improve our ability to use real world data to characterize patient populations, construct population level estimates relating exposures to health outcomes, and to enhance clinical decision making through improved patient-level predictions. More information and an application link are available here.

 FDA/CDER’s Division of Hepatology and Nutrition is seeking a clinician with bioinformatics or biostatistics training to work with the Drug-Induced Liver Injury (DILI) Team to evaluate large datasets of liver-related data, collaborate on the Team’s review of drugs with hepatotoxicity signals, and help develop informatics-based processes in DILI evaluation across the Agency. Contact Judy Racoosin at judith.racoosin@fda.hhs.gov for information about the application process (that will be through USAJOBS).

• Andrew Williams recently announced two exciting new openings at Tufts Medicine. 1) Senior Project Manager for a multisite multiyear grant standardizing critical care EHR and waveform data. (CHoRUS Bridge2AI) 2) Lead software developer and research data warehouse manager for Tufts Medicine’s OMOP instance and related services. Remote work is possible for both positions. If you have questions, please reach out to Andrew at awilliams15@tuftsmedicalcenter.org.

 The Johns Hopkins OHDSI team has just put out an opening for a data scientist/statistical engineer position. The candidate is expected to help create further synergy between the domain expertise of Johns Hopkins’s Precision Medicine Centers of Excellence and the extensive health data network provided through our OHDSI collaboration. More details and an application link are available here.

OHDSI UPDATES

• If you missed the symposium plenary session on Objective Diagnostics: A pathway to provably reliable evidence, or if you wanted to engage in a discussion about the content, please join our OHDSI2022 Plenary Discussion on Friday, Dec. 9, from 10 am – 12 pm ET. We will rewatch the video in sections and take breaks to engage in Q&A with presenters and other collaborators involved in the work. Click here for the meeting link.

• The latest edition of OHDSI’s official newsletter, The Journey, is now available. It includes information on recent open-source developments, the OHDSI APAC Symposium, recent publications and presentations, and other community updates. If you don’t get the newsletter monthly in your inbox, you can subscribe here.

• Patrick Ryan introduced the OMOP Common Data Model (CDM) Entity-Relationship Diagram (ERD) Challenge on the forums recently. All members of the OHDSI community are welcome and encouraged to submit their entries of the best ERD for the OMOP CDM to this forum post (or to the CDM Workgroup MS Teams site) by Tuesday, Dec 13. One winner will be selected by a committee from the CDM workgroup, and announced on OHDSI’s last community call of the year on Dec 20.

OHDSI Social Showcase

 The #OHDSISocialShowcase continues this week, as all the research from the OHDSI Symposium collaborator showcase will be presented on the Twitter and LinkedIn social feeds over the next several months. You can see the research and the respective leads that will be shared this week.

Monday: An Evaluation of the Impact of Vocabulary Evolution on Established Phenotypes (Frank DeFalco)

Tuesday: Transitioning ANANKE to OMOP2OBO for more robust NLP extraction and knowledge graph data representation leveraging the OHDSI vocabulary (Juan Banda)

Wednesday: Building organizational capacity for observational research within a health system (Mary Grace Bowring)

Thursday: Topic Modeling of Clinical Notes for Patients with Infectious Disease using Latent Dirichlet Allocation after Deidentification of Protected Health Information (Junhyuk Chang)

Friday: ohdsitargets – An R package for building OHDSI study pipelines using targets (Adam Black)

OHDSI MSTEAMS

Accessing MSTeams: To join OHDSI Teams, please fill out this form: Join OHDSI Teams
If you are already in the OHDSI Teams environment and you would like to join work groups in teams, please fill out this form: Join Workgroups, Chapters, and Studies

Teams Best Practices and Guidance: For guidance on MS Teams, please check out this link
OHDSI-MICROSOFT-TEAMS-BEST-PRACTICES-1.pdf

Duplicate email removal from OHDSI Teams: As you should always be using one email in OHDSI Teams when joining all workgroups, you may remove duplicate emails by filling out this form

Please continue to collaborate in our MS Teams environment, check out the OHDSI website and forums , and follow us on all platforms, including Twitter and LinkedIn to get continued updates and information on everything happening in our community